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Table 9 Correlation between Child Health and Illness Profile-Child Edition and ADHD-Rating Scale hyperactive/impulsive subscore, by age groups based on data of all 5 trials.

From: Differences between children and adolescents in treatment response to atomoxetine and the correlation between health-related quality of life and Attention Deficit/Hyperactivity Disorder core symptoms: Meta-analysis of five atomoxetine trials

CHIP-CE

Baseline

Endpoint

Change from baseline

Children n = 570-609

r

95% CI

r

95% CI

r

95% CI

Total Score

-0.295

-0.365 to -0.224

-0.482

-0.545 to -0.419

-0.478

-0.541 to -0.414

Satisfaction Domain

-0.005

-0.092 to 0.082

-0.191

-0.269 to -0.113

-0.278

-0.357 to -0.198

Satisfaction with Health

0.077

-0.013 to 0.167

-0.092

-0.171 to -0.014

-0.189

-0.275 to -0.104

Satisfaction with Self

-0.093

-0.173 to -0.013

-0.261

-0.338 to -0.185

-0.305

-0.381 to -0.228

Comfort Domain

-0.154

-0.232 to -0.075

-0.253

-0.328 to -0.179

-0.326

-0.394 to -0.258

Physical Comfort

-0.012

-0.091 to 0.068

-0.039

-0.114 to 0.037

-0.129

-0.207 to -0.052

Emotional Comfort

-0.249

-0.319 to -0.179

-0.373

-0.444 to -0.302

-0.402

-0.466 to -0.337

Restricted Activity

0.018

-0.068 to 0.105

-0.035

-0.117 to 0.046

-0.074

-0.147 to -0.000

Risk Avoidance Domain

-0.524

-0.573 to -0.475

-0.613

-0.670 to -0.557

-0.522

-0.585 to -0.459

Individual Risk Avoidance

-0.478

-0.530 to -0.425

-0.507

-0.571 to -0.444

-0.389

-0.468 to -0.310

Threats to Achievement

-0.478

-0.531 to -0.425

-0.587

-0.643 to -0.531

-0.502

-0.566 to -0.437

Resilience Domain

-0.032

-0.107 to 0.043

-0.259

-0.335 to -0.183

-0.163

-0.247 to -0.079

Family Involvement

-0.026

-0.100 to 0.047

-0.179

-0.256 to -0.101

-0.128

-0.206 to -0.051

Physical Activity

0.174

0.096 to 0.252

-0.057

-0.138 to 0.024

-0.018

-0.095 to 0.058

Social Problem Solving

-0.163

-0.244 to -0.082

-0.263

-0.341 to -0.184

-0.168

-0.265 to -0.070

Achievement Domain

-0.196

-0.270 to -0.121

-0.412

-0.482 to -0.342

-0.413

-0.486 to -0.340

Academic Performance

-0.089

-0.162 to -0.015

-0.361

-0.436 to -0.285

-0.376

-0.453 to -0.299

Peer Relations

-0.210

-0.286 to -0.134

-0.295

-0.369 to -0.221

-0.287

-0.368 to -0.207

Adolescents n = 165-181

      

Total Score

-0.347

-0.490 to -0.203

-0.481

-0.595 to -0.368

-0.436

-0.566 to -0.306

Satisfaction Domain

-0.041

-0.189 to 0.107

-0.143

-0.289 to 0.004

-0.219

-0.382 to -0.056

Satisfaction with Health

0.008

-0.141 to 0.157

-0.080

-0.228 to 0.067

-0.108

-0.267 to 0.050

Satisfaction with Self

-0.078

-0.216 to 0.059

-0.178

-0.322 to -0.034

-0.269

-0.422 to -0.115

Comfort Domain

-0.208

-0.349 to -0.067

-0.297

-0.429 to -0.166

-0.286

-0.428 to -0.144

Physical Comfort

-0.049

-0.177 to 0.080

-0.064

-0.213 to 0.085

-0.129

-0.273 to 0.016

Emotional Comfort

-0.302

-0.441 to -0.164

-0.426

-0.540 to -0.312

-0.371

-0.496 to -0.246

Restricted Activity

-0.005

-0.144 to 0.135

-0.079

-0.228 to 0.069

-0.049

-0.209 to 0.110

Risk Avoidance Domain

-0.568

-0.671 to -0.466

-0.593

-0.701 to -0.485

-0.359

-0.492 to -0.226

Individual Risk Avoidance

-0.474

-0.596 to -0.352

-0.484

-0.621 to -0.347

-0.181

-0.328 to -0.035

Threats to Achievement

-0.531

-0.633 to -0.430

-0.570

-0.673 to -0.468

-0.345

-0.476 to -0.215

Resilience Domain

-0.181

-0.322 to -0.040

-0.235

-0.370 to -0.100

-0.294

-0.432 to -0.156

Family Involvement

-0.085

-0.215 to 0.046

-0.198

-0.324 to -0.072

-0.181

-0.328 to -0.035

Physical Activity

0.091

-0.051 to 0.233

0.059

-0.083 to 0.201

-0.071

-0.210 to 0.068

Social Problem Solving

-0.292

-0.422 to -0.161

-0.311

-0.454 to -0.168

-0.309

-0.434 to -0.185

Achievement Domain

-0.233

-0.377 to -0.089

-0.472

-0.583 to -0.362

-0.471

-0.595 to -0.347

Academic Performance

-0.097

-0.244 to 0.050

-0.495

-0.603 to -0.388

-0.421

-0.557 to -0.284

Peer Relations

-0.244

-0.383 to -0.104

-0.264

-0.406 to -0.123

-0.282

-0.410 to -0.154

  1. Abbreviations: CHIP-CE, Child Health and Illness Profile-Child Edition; ADHD-RS, Attention Deficit/Hyperactivity Disorder Rating Scale; CI, confidence interval; r, Pearson's correlation coefficient
  2. Correlations larger than 0.3 were marked in bold to improve readability.