Psychiatric disorders in term-born children with marginally low birth weight: a population-based study

Table 3 Univariate and multivariate analyses of subsequent psychiatric disease incidences in full term infants with or without the diagnosis of low birth weight (birth weight between 2000 to 2500 g) (N = 100,120)

variable	MLBW (n = 50,060)	No MLBW (n = 50,060)	Univariate model				Multivariate model^a
variable	No. of participants	No. of participants	Crude HR	(95% CI)^b		p value	Adjusted HR	(95% CI)^b		p value
Any psychiatric disorders	8660	6695	1.36	1.36	1.40	< 0.001	1.33	1.29	1.37	< 0.001
Specific delay in development or mental retardation	7109	5290	1.40	1.35	1.46	<0 .001	1.38	1.33	1.43	<0 .001
Attention deficit and hyperactivity disorder	3359	2690	1.27	1.20	1.34	<0 .001	1.26	1.20	1.33	< 0.001
Adjustment disorders	240	228	1.05	0.88	1.26	0.58	1.05	0.88	1.26	0.58
Afftve disorders	12	8	1.50	0.61	3.67	0.37	1.50	0.61	3.67	0.37
Anxiety disorders	319	292	1.09	0.93	1.28	0.27	1.09	0.93	1.28	0.27
Autism spectrum disorders	854	677	1.27	1.14	1.40	< 0.001	1.26	1.14	1.40	<0 .001
Conduct disorders	234	188	1.25	1.03	1.51	0.03	1.25	1.03	1.51	0.02
Emotional disturbance	704	622	1.13	1.02	1.26	0.02	1.13	1.02	1.26	0.02
Personality disorders	14	6	2.33	0.90	6.07	0.08	2.33	0.90	6.07	0.08
Psychosis	5	0	1.50	0.25	8.98	0.66	1.50	0.25	8.99	0.66
Schizophrenia	0	0

MLBW marginally low birthweight, defined as term-born infants with birth weight between 2000 and 2499 grams. No MLBW: term-born infants with birth weight 2500 grams
^a Multivariate Cox proportional hazard model, adjusted for all covariates from Table 2. ^b No MLBW is reference group

ISSN: 1753-2000