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Table 2 Movement Disorder Ratings in the Total Study Population

From: Evaluating movement disorders in pediatric patients receiving risperidone: a comparison of spontaneous reports and research criteria for TD

ESRS Subscale or Item Possible Range of Scores Mean Baseline Score (± SD) Mean Endpoint Score (± SD) P Value for Change From Baseline* (df, test value)
Subjective overall rating (items 1–11) 0–33 0.80 ± 1.59 0.60 ± 1.39 0.0002 (667, T = -3.73)
Physician's examination for parkinsonism (items 13–30) 0–108 1.07 ± 3.18 0.88 ± 2.35 0.0596 (667, T = -1.89)
Physician's examination for akathisia (item 28) 0–6 0.41 ± 1.07 0.19 ± 0.70 < 0.0001 (667, T = -5.72)
Physician's examination for dyskinesia (items 51–57) 0–42 0.17 ± 1.02 0.12 ± 0.73 0.2155 (617, T = -1.24)
CGI of severity of parkinsonism (item 59) 0–8 0.08 ± 0.46 0.11 ± 0.45 0.2331 (667, T = 1.19)
CGI of severity of dystonia (item 60) 0–8 0.05 ± 0.37 0.04 ± 0.31 0.7534 (667, T = -0.31)
CGI of severity of dyskinesia (item 58) 0–8 0.06 ± 0.39 0.08 ± 0.44 0.3535 (667, T = 0.93)
  1. ESRS indicates Extrapyramidal Symptom Rating Scale; SD, standard deviation; CGI, Clinical Global Impressions.
  2. *Two-sided P value for paired T test.