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Table 2 Movement Disorder Ratings in the Total Study Population

From: Evaluating movement disorders in pediatric patients receiving risperidone: a comparison of spontaneous reports and research criteria for TD

ESRS Subscale or Item

Possible Range of Scores

Mean Baseline Score (± SD)

Mean Endpoint Score (± SD)

P Value for Change From Baseline*

(df, test value)

Subjective overall rating (items 1–11)

0–33

0.80 ± 1.59

0.60 ± 1.39

0.0002

(667, T = -3.73)

Physician's examination for parkinsonism (items 13–30)

0–108

1.07 ± 3.18

0.88 ± 2.35

0.0596

(667, T = -1.89)

Physician's examination for akathisia (item 28)

0–6

0.41 ± 1.07

0.19 ± 0.70

< 0.0001

(667, T = -5.72)

Physician's examination for dyskinesia (items 51–57)

0–42

0.17 ± 1.02

0.12 ± 0.73

0.2155

(617, T = -1.24)

CGI of severity of parkinsonism (item 59)

0–8

0.08 ± 0.46

0.11 ± 0.45

0.2331

(667, T = 1.19)

CGI of severity of dystonia (item 60)

0–8

0.05 ± 0.37

0.04 ± 0.31

0.7534

(667, T = -0.31)

CGI of severity of dyskinesia (item 58)

0–8

0.06 ± 0.39

0.08 ± 0.44

0.3535

(667, T = 0.93)

  1. ESRS indicates Extrapyramidal Symptom Rating Scale; SD, standard deviation; CGI, Clinical Global Impressions.
  2. *Two-sided P value for paired T test.