ESRS Subscale or Item | Possible Range of Scores | Mean Baseline Score (± SD) | Mean Endpoint Score (± SD) | P Value for Change From Baseline* (df, test value) |
---|---|---|---|---|
Subjective overall rating (items 1–11) | 0–33 | 0.80 ± 1.59 | 0.60 ± 1.39 | 0.0002 (667, T = -3.73) |
Physician's examination for parkinsonism (items 13–30) | 0–108 | 1.07 ± 3.18 | 0.88 ± 2.35 | 0.0596 (667, T = -1.89) |
Physician's examination for akathisia (item 28) | 0–6 | 0.41 ± 1.07 | 0.19 ± 0.70 | < 0.0001 (667, T = -5.72) |
Physician's examination for dyskinesia (items 51–57) | 0–42 | 0.17 ± 1.02 | 0.12 ± 0.73 | 0.2155 (617, T = -1.24) |
CGI of severity of parkinsonism (item 59) | 0–8 | 0.08 ± 0.46 | 0.11 ± 0.45 | 0.2331 (667, T = 1.19) |
CGI of severity of dystonia (item 60) | 0–8 | 0.05 ± 0.37 | 0.04 ± 0.31 | 0.7534 (667, T = -0.31) |
CGI of severity of dyskinesia (item 58) | 0–8 | 0.06 ± 0.39 | 0.08 ± 0.44 | 0.3535 (667, T = 0.93) |