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Table 4 Baseline ratings and change from baseline at weeks 8 and 24

From: Emotional well-being in children and adolescents treated with atomoxetine for attention-deficit/hyperactivity disorder: Findings from a patient, parent and physician perspective using items from the pediatric adverse event rating scale (PAERS)

Item Week Physician rating Parent rating Patient rating
   Mean 95% CI SD Mean 95% CI SD Mean 95% CI SD
Items relating to depressed mood
8 0 0.32 0.26 to 0.39 0.71 0.54 0.45 to 0.63 0.93 0.33 0.26 to 0.40 0.75
  Ch 8 -0.14 -0.22 to -0.05 0.77 -0.25 -0.35 to -0.15 0.96 -0.20 -0.28 to -0.12 0.76
  Ch 24 -0.20 -0.29 to -0.11 0.71 -0.33 -0.45 to -0.21 0.97 -0.23 -0.32 to -0.13 0.75
32 0 0.50 0.42 to 0.58 0.83 0.81 0.71 to 0.91 1.04 0.44 0.34 to 0.53 0.95
  Ch 8 -0.18 -0.28 to -0.09 0.87 -0.31 -0.43 to -0.19 1.08 -0.23 -0.34 to -0.12 0.99
  Ch 24 -0.26 -0.37 to -0.15 0.90 -0.44 -0.57 to -0.31 1.10 -0.15 -0.28 to -0.02 1.03
39 0 0.48 0.40 to 0.57 0.91 0.78 0.68 to 0.89 1.07 0.47 0.38 to 0.56 0.94
  Ch 8 -0.17 -0.27 to -0.07 0.90 -0.28 -0.40 to -0.16 1.11 -0.28 -0.38 to -0.18 092
  Ch 24 -0.28 -0.39 to -0.17 0.90 -0.36 -0.49 to -0.22 1.14 -0.31 -0.43 to -0.19 1.01
Items relating to self-harm
20 0 0.07 0.03 to 0.10 0.38 0.11 0.06 to 0.16 0.51 0.08 0.04 to 0.11 0.40
  Ch 8 -0.01 -0.05 to 0.03 0.37 -0.02 -0.07 to 0.02 0.43 0.00 -0.05 to 0.06 0.51
  Ch 24 -0.02 -0.06 to 0.02 0.32 -0.03 -0.09 to 0.02 0.42 -0.02 -0.06 to 0.02 0.34
43 0 0.07 0.03 to 0.10 0.37 0.11 0.06 to 0.16 0.52 0.08 0.04 to 0.12 0.40
  Ch 8 -0.02 -0.07 to 0.03 0.44 -0.01 -0.06 to 0.04 0.47 0.02 -0.02 to 0.06 0.37
  Ch 24 -0.02 -0.06 to 0.03 0.37 -0.03 -0.08 to 0.01 0.39 0.00 -0.05 to 0.05 0.42
Items relating to irritability/agitation
16 0 0.98 0.87 to 1.08 1.10 1.27 1.16 to 1.39 1.20 0.61 0.51 to 0.70 1.01
  Ch 8 -0.68 -0.80 to -0.55 1.17 -0.78 -0.91 to -0.65 1.18 -0.36 -0.48 to -0.25 1.07
  Ch 24 -0.69 -0.83 to -0.55 1.16 -0.80 -0.94 to -0.65 1.19 -0.41 -0.54 to -0.27 1.10
26 0 1.41 1.30 to 1.53 1.22 1.79 1.67 to 1.92 1.27 0.66 0.56 to 0.77 1.09
  Ch 8 -0.97 -1.10 to -0.83 1.24 -1.09 -1.24 to -0.95 1.34 -0.42 -0.52 to -0.31 1.00
  Ch 24 -0.93 -1.07 to -0.79 1.18 -1.10 -1.26 to -0.94 1.31 -0.43 -0.56 to -0.30 1.08
42 0 1.32 1.20 to 1.45 1.26 2.00 1.88 to 2.12 1.22 0.93 0.81 to 1.04 1.22
  Ch 8 -0.52 -0.64 to -0.39 1.17 -0.72 -0.86 to -0.57 1.34 -0.43 -0.57 to -0.29 1.26
  Ch 24 -0.55 -0.70 to -0.41 1.18 -0.85 -1.02 to -0.68 1.38 -0.46 -0.62 to -0.30 1.33
Item relating to drowsiness
37 0 0.25 0.19 to 0.30 0.61 0.43 0.35 to 0.50 0.81 0.40 0.32 – 0.48 0.85
  Ch 8 -0.08 -0.15 to 0.00 0.71 -0.16 -0.25 to -0.07 0.83 -0.16 -0.26 to -0.07 0.88
  Ch 24 -0.17 -0.24 to -0.10 0.59 -0.25 -0.36 to -0.14 0.88 -0.20 -0.31 to -0.09 0.86
Item relating to euphoria
38 0 0.35 0.28 to 0.43 0.77 0.65 0.55 to 0.74 1.00 1.06 0.93 to 1.19 1.33
  Ch 8 -0.14 -0.22 to -0.05 0.83 -0.32 -0.43 to -0.20 1.05 -0.40 -0.56 to -0.25 1.41
  Ch 24 -0.15 -0.25 to -0.06 0.75 -0.40 -0.51 to -0.29 0.92 -0.43 -0.58 to -0.28 1.24
  1. Items: 8 = feeling withdrawn or numb; 32 = sad or low mood/unhappy; 39 = not interested/no enthusiasm; 20 = trying to hurt him or her self; 43 = thinking about or wanting to hurt self; 16 = nervous, tense, or uptight, 26 = feeling restless or keyed up; 42 = angry or irritable/in a bad mood; 37 = drowsy or "out of it, 38 = unusually good mood/super happy. Abbreviations: 0 = Week 0 (Baseline); Ch 8 = change to week 8, Ch 24 = change to Week 24; CI = confidence interval; SD = standard deviation.