From: Lack of association of genetic variants in genes of the endocannabinoid system with anorexia nervosa
Gene | SNP^{1,2} | Alleles^{3} major/minor | Location Exchange | N^{4} | Genotypes (%)^{5} | Allele frequ.^{6} | Transm. rate^{7} | p-value^{8} |
---|---|---|---|---|---|---|---|---|
A/A 26 (42.62) | A: 0.64 | |||||||
A/G 26 (42.62) | ||||||||
CNR1 | rs2180619 | -22,959A/G | Putative promoter | 61 | G/G 9 (14.75) | G: 0.36 | 0.49 (G) | 1.00 |
A/A 16 (26.23) | A: 0.55 | |||||||
A/T 35 (57.38) | ||||||||
CNR1 | rs806379 | -6,274A/T | Intron 2 | 61 | T/T 10 (16.39) | T: 0.45 | 0.52 (T) | 0.90 |
T/T 43 (70.49) | T: 0.84 | |||||||
T/G 16 (26.23) | ||||||||
CNR1 | rs1535255 | -6,215T/G | Intron 2 | 61 | G/G 2 (3.28) | G: 0.16 | 0.50 (G) | 1.00 |
T/T 43 (70.49) | T: 0.84 | |||||||
T/C 16 (26.23) | ||||||||
CNR1 | rs2023239 | -5,489T/C |
Exon 3 Non-coding | 61 | C/C 2 (3.28) | C: 0.16 | 0.50 (C) | 1.00 |
G/G 38 (41.76) | G: 0.65 | |||||||
G/A 43 (47.25) | ||||||||
CNR1 | rs1049353 | 1,359G/A |
Exon 4 Thr453Thr | 91 | A/A 10 (10.99) | A: 0.35 | 0.59 (A) | 0.11 |
G/G 33 (54.10) | G: 0.75 | |||||||
G/A 26 (42.62) | ||||||||
FAAH | rs932816 | -272G/A |
Putative promoter | 61 | A/A 2 (3.28) | A: 0.25 | 0.39 (A) | 0.13 |
C/C 40 (66.67) | C: 0.80 | |||||||
C/A 16 (26.67) | ||||||||
FAAH | rs324420 | 10,741C/A |
Exon 3 Thr129Pro | 60 | A/A 4 (6.67) | A: 0.20 | 0.56 (A) | 0.61 |
G/G 49 (80.33) | G: 0.89 | |||||||
G/A 11 (18.03) | ||||||||
FAAH | rs324419 | 11,966G/A |
Exon 7 Cys299Cys | 61 | A/A 1 (1.64) | A: 0.11 | 0.59 (A) | 0.52 |
G/G 60 (98.36) | G: 0.99 | |||||||
G/A 1 (1.64) | ||||||||
FAAH | rs873978 | 13,883G/A | Intron 7 | 61 | A/A 0 (0.00) | A: 0.01 | 1.00 (A) | 1.00 |
C/C 34 (56.67) | C: 0.73 | |||||||
C/A 20 (33.33) | ||||||||
FAAH | rs2295632 | 19,542C/A | 3'UTR | 60 | A/A 6 (10.0) | A: 0.27 | 0.42 (A) | 0.42 |
G/G 34 (56.67) | G: 0.75 | |||||||
G/A 22 (36.67) | ||||||||
NAAA | rs2292534 | 368A/G | Intron 1 | 60 | A/A 4 (6.67) | A: 0.25 | 0.57 (A) | 0.42 |
A/A 38 (62.30) | A: 0.78 | |||||||
A/T 19 (31.15) | ||||||||
NAAA | rs4859567 | 9,263A/T | Intron 3 | 61 | T/T 4 (6.56) | T: 0.22 | 0.43 (T) | 0.42 |
G/G 36 (60.00) | G: 0.78 | |||||||
G/T 21 (35.00) | ||||||||
NAAA | rs10518142 | 19,229G/T | Intron 5 | 60 | T/T 3 (5.00) | T: 0.22 | 0.63 (T) | 0.13 |
C/C 22 (36.07) | C: 0.61 | |||||||
C/T 31 (50.82) | ||||||||
NAAA | rs6819442 | 22,995C/T | Intron 9 | 61 | T/T 8 (13.11) | T: 0.39 | 0.56 (T) | 0.42 |
T/T 36 (59.02) | T: 0.75 | |||||||
T/A 19 (31.15) | ||||||||
MGLL | rs893294 | 121,143T/A | Intron 8 | 61 | A/A 6 (9.84) | A: 0.25 | 0.54 (A) | 0.75 |