Morning and evening behavior in children and adolescents treated with atomoxetine once daily for Attention-Deficit/Hyperactivity Disorder (ADHD): Findings from two 24-week, open-label studies

Wehmeier, Peter M; Dittmann, Ralf W; Schacht, Alexander; Helsberg, Karin; Lehmkuhl, Gerd

doi:10.1186/1753-2000-3-5

Child and Adolescent Psychiatry and Mental Health

Table 4 Correlation of WREMB-R evening and morning subscores with GIPD scores for evening and morning items (Pearson's Correlation Coefficients and 95% CI; OC)

From: Morning and evening behavior in children and adolescents treated with atomoxetine once daily for Attention-Deficit/Hyperactivity Disorder (ADHD): Findings from two 24-week, open-label studies

	Correlation with WREMB-R evening subscore
	GIPD evening (patient-rated)		GIPD evening (parent-rated)		GIPD evening (physician-rated)
Week	N	Correlation	N	Correlation	N	Correlation
0	416	0.321 [0.231–0.404]	413	0.537 [0.464–0.602]	414	0.695 [0.641–0.741]
1	412	0.276 [0.184–0.363]	401	0.625 [0.561–0.681]	410	0.717 [0.665–0.760]
2	397	0.337 [0.247–0.421]	392	0.686 [0.630–0.735]	399	0.790 [0.750–0.824]
4	383	0.348 [0.257–0.433]	382	0.672 [0.612–0.723]	387	0.767 [0.722–0.805]
6	365	0.398 [0.307–0.480]	359	0.774 [0.728–0.812]	368	0.790 [0.748–0.826]
8	326	0.270 [0.166–0.368]	324	0.731 [0.675–0.778]	326	0.772 [0.723–0.812]
12	314	0.177 [0.067–0.282]	312	0.684 [0.619–0.738]	317	0.707 [0.647–0.758]
16	271	0.347 [0.237–0.447]	268	0.683 [0.612–0.741]	274	0.764 [0.709–0.809]
24	259	0.336 [0.223–0.440]	257	0.733 [0.670–0.784]	261	0.767 [0.711–0.812]
all visits pooled	3143	0.351 [0.320–0.382]	3108	0.708 [0.690–0.725]	3156	0.790 [0.776–0.803]
	Correlation with WREMB-R morning subscore
	GIPD morning (patient-rated)		GIPD morning (parent-rated)		GIPD morning (physician-rated)
	N	Correlation	N	Correlation	N	Correlation
0	416	0.258 [0.166–0.346]	413	0.612 [0.547–0.668]	414	0.714 [0.663–0.758]
1	411	0.442 [0.361–0.517]	400	0.644 [0.582–0.698]	409	0.727 [0.677–0.769]
2	397	0.318 [0.226–0.403]	392	0.699 [0.644–0.746]	399	0.760 [0.714–0.798]
4	383	0.311 [0.217–0.398]	382	0.754 [0.706–0.794]	387	0.742 [0.693–0.783]
6	365	0.297 [0.200–0.388]	359	0.738 [0.686–0.781]	368	0.778 [0.734–0.815]
8	326	0.331 [0.231–0.424]	324	0.677 [0.612–0.731]	326	0.776 [0.729–0.816]
12	314	0.332 [0.229–0.426]	312	0.734 [0.678–0.781]	317	0.791 [0.746–0.829]
16	271	0.361 [0.252–0.460]	268	0.710 [0.645–0.764]	274	0.779 [0.727–0.821]
24	259	0.313 [0.198–0.418]	257	0.734 [0.671–0.785]	261	0.778 [0.725–0.822]
all visits pooled	3142	0.371 [0.341–0.401]	3107	0.719 [0.701–0.735]	3155	0.786 [0.772–0.799]

CI = confidence interval, GIPD = Global Impression of Perceived Difficulties, OC = observed cases analysis, WREMB-R = Weekly Ratings of Evening and Morning Behavior-Revised.

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ISSN: 1753-2000

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