Table 2 List of Exclusion Criteria
From: Child/Adolescent Anxiety Multimodal Study (CAMS): rationale, design, and methods
Exclusion Criteria | Rationale |
|---|---|
The following Axis I disorders: | These disorders require treatments not provided within the context of the CAMS trial |
   • Major Depressive Disorder |  |
   • Bipolar Disorder |  |
   • Psychotic Disorder |  |
   • Pervasive Developmental Disorder |  |
   • Uncontrolled ADHD (combined or primarily hyperactive type) |  |
   • Eating Disorders |  |
   • Substance Use Disorders |  |
Any Axis I disorder (excluding those mentioned above), with an ADIS CSR ≥ to the CSR of the disorders of interest (SAD, GAD, SoP) | Disorders of interest (SAD, SoP, GAD) must be the most severe and disabling conditions affecting the child |
School refusal behavior characterized by missing > 25% of school days in most recent term | May require additional or different treatments |
Suicidal or homicidal | Unethical to randomize to PBO |
Two previous failed trials of an SSRI or a failed trial of an adequate course of CBT for the disorders of interest | Not likely to respond to study treatments; may require additional treatments |
Intolerance to sertraline | Risk of side effects/adverse events |
Confounding medical condition | Potential medical risk or confounding issue |
Pregnancy | Potential risk of medication effects to fetus |
Child or adolescent does not speak English | Cannot complete study assessments and CBT |