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Table 7 Correlation between Child Health and Illness Profile-Child Edition and ADHD-Rating Scale total score, by age groups based on data of all 5 trials.

From: Differences between children and adolescents in treatment response to atomoxetine and the correlation between health-related quality of life and Attention Deficit/Hyperactivity Disorder core symptoms: Meta-analysis of five atomoxetine trials

 

Baseline

Endpoint

Change from baseline

CHIP-CE

n

r

95% CI

N

r

95% CI

n

r

95% CI

Children

         

Total Score

609

-0.350

-0.418 to -0.282

598

-0.527

-0.589 to -0.466

596

-0.534

-0.595 to -0.474

Satisfaction Domain

604

-0.070

-0.153 to 0.013

598

-0.250

-0.327 to -0.174

591

-0.319

-0.396 to -0.242

Satisfaction with Health

604

0.006

-0.079 to 0.090

598

-0.153

-0.231 to -0.075

591

-0.228

-0.313 to -0.144

Satisfaction with Self

604

-0.133

-0.213 to -0.053

598

-0.305

-0.380 to -0.229

591

-0.340

-0.415 to -0.266

Comfort Domain

609

-0.204

-0.279 to -0.129

598

-0.301

-0.374 to -0.228

596

-0.359

-0.426 to -0.292

Physical Comfort

609

-0.039

-0.117 to 0.039

598

-0.099

-0.175 to -0.022

596

-0.149

-0.224 to -0.074

Emotional Comfort

609

-0.299

-0.368 to -0.230

598

-0.397

-0.468 to -0.032

596

-0.439

-0.503 to -0.375

Restricted Activity

586

-0.019

-0.101 to 0.062

594

-0.068

-0.148 to 0.011

570

-0.080

-0.157 to -0.003

Risk Avoidance Domain

608

-0.517

-0.572 to -0.462

598

-0.591

-0.649 to -0.533

595

-0.545

-0.608 to -0.482

Individual Risk Avoidance

609

-0.494

-0.548 to -0.439

597

-0.478

-0.545 to -0.411

595

-0.401

-0.481 to -0.321

Threats to Achievement

607

-0.459

-0.519 to -0.398

598

-0.571

-0.628 to -0.514

594

-0.526

-0.590 to -0.463

Resilience Domain

609

-0.042

-0.116 to 0.033

597

-0.284

-0.361 to -0.208

595

-0.205

-0.289 to -0.120

Family Involvement

609

-0.018

-0.093 to 0.057

597

-0.195

-0.272 to -0.118

595

-0.163

-0.240 to -0.087

Physical Activity

609

0.150

0.072 to 0.227

597

-0.103

-0.183 to -0.023

595

-0.043

-0.120 to 0.034

Social Problem Solving

606

-0.170

-0.251 to -0.089

597

-0.261

-0.341 -0.180

592

-0.193

-0.292 to -0.095

Achievement Domain

598

-0.273

-0.345 to -0.201

590

-0.467

-0.535 to -0.399

579

-0.482

-0.550 to -0.413

Academic Performance

598

-0.206

-0.281 to -0.130

589

-0.449

-0.521 to -0.378

578

-0.443

-0.517 to -0.369

Peer Relations

607

-0.204

-0.281 to -0.127

598

-0.288

-0.363 to -0.213

594

-0.321

-0.400 to -0.242

Adolescents

         

Total Score

181

-0.349

-0.485 to -0.213

177

-0.535

-0.637 to -0.434

176

-0.503

-0.624 to -0.383

Satisfaction Domain

181

-0.050

-0.188 to 0.088

177

-0.203

-0.345 to -0.061

176

-0.275

-0.435 to -0.115

Satisfaction with Health

180

-0.012

-0.154 to 0.129

177

-0.127

-0.267 to 0.013

176

-0.162

-0.324 to -0.000

Satisfaction with Self

181

-0.074

-0.206 to 0.059

177

-0.239

-0.382 to -0.096

176

-0.310

-0.465 to -0.156

Comfort Domain

180

-0.194

-0.325 to -0.062

177

-0.289

-0.430 to -0.148

175

-0.305

-0.448 to -0.163

Physical Comfort

180

-0.050

-0.182 to 0.082

177

-0.064

-0.208 to 0.080

176

-0.143

-0.293 to 0.007

Emotional Comfort

179

-0.260

-0.392 to -0.128

177

-0.399

-0.526 to -0.272

174

-0.384

-0.505 to -0.262

Restricted Activity

172

-0.047

-0.187 to 0.093

173

-0.107

-0.243 to 0.029

165

-0.063

-0.218 to 0.093

Risk Avoidance Domain

180

-0.537

-0.650 to -0.424

176

-0.567

-0.685 to -0.449

174

-0.384

-0.515 to -0.254

Individual Risk Avoidance

180

-0.446

-0.574 to -0.318

177

-0.424

-0.571 to -0.277

175

-0.182

-0.327 to -0.037

Threats to Achievement

180

-0.504

-0.618 to -0.389

176

-0.570

-0.675 to -0.466

174

-0.381

-0.502 to -0.261

Resilience Domain

180

-0.190

-0.331 to -0.050

177

-0.290

-0.419 to -0.162

175

-0.329

-0.470 to -0.188

Family Involvement

179

-0.023

-0.158 to 0.113

177

-0.171

-0.306 to -0.036

174

-0.207

-0.351 to -0.063

Physical Activity

179

0.029

-0.114 to 0.171

177

0.003

-0.137 to 0.142

175

-0.095

-0.242 to 0.051

Social Problem Solving

180

-0.320

-0.446 to -0.194

176

-0.388

-0.516 to -0.259

174

-0.337

-0.458 to -0.216

Achievement Domain

176

-0.275

-0.408 to -0.142

171

-0.562

-0.661 to -0.462

166

-0.558

-0.672 to -0.444

Academic Performance

175

-0.199

-0.350 to -0.048

171

-0.610

-0.705 to -0.515

165

-0.517

-0.642 to -0.392

Peer Relations

180

-0.223

-0.366 to -0.080

177

-0.296

-0.436 to -0.156

175

-0.331

-0.461 to -0.201

  1. Abbreviations: CHIP-CE, Child Health and Illness Profile-Child Edition; ADHD-RS, Attention Deficit/Hyperactivity Disorder Rating Scale; CI, confidence interval; r, Pearson's correlation coefficient