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Table 8 Correlation between Child Health and Illness Profile-Child Edition and ADHD-Rating Scale inattentive subscore, by age groups based on data of all 5 trials.

From: Differences between children and adolescents in treatment response to atomoxetine and the correlation between health-related quality of life and Attention Deficit/Hyperactivity Disorder core symptoms: Meta-analysis of five atomoxetine trials

CHIP-CE

Baseline

Endpoint

Change from baseline

 

R

95% CI

r

95% CI

r

95% CI

Children n = 570-609

      

Total Score

-0.275

-0.345 to -0.205

-0.513

-0.575 to -0.452

-0.535

-0.595 to -0.475

Satisfaction Domain

-0.137

-0.213 to -0.060

-0.285

-0.361 to -0.209

-0.327

-0.403 to -0.252

Satisfaction with Health

-0.106

-0.183 to -0.028

-0.201

-0.278 to -0.124

-0.243

-0.326 to -0.159

Satisfaction with Self

-0.134

-0.210 to -0.058

-0.315

-0.390 to -0.240

-0.340

-0.412 to -0.268

Comfort Domain

-0.188

-0.260 to -0.116

-0.317

-0.391 to -0.243

-0.354

-0.423 to -0.285

Physical Comfort

-0.062

-0.141 to 0.016

-0.152

-0.230 to -0.073

-0.153

-0.227 to -0.079

Emotional Comfort

-0.240

-0.310 to -0.169

-0.376

-0.448 to -0.305

-0.430

-0.495 to -0.365

Restricted Activity

-0.068

-0.145 to 0.010

-0.095

-0.174 to -0.017

-0.078

-0.161 to 0.004

Risk Avoidance Domain

-0.273

-0.343 to -0.204

-0.496

-0.562 to -0.431

-0.511

-0.576 to -0.446

Individual Risk Avoidance

-0.293

-0.360 to -0.226

-0.390

-0.462 to -0.317

-0.372

-0.452 to -0.292

Threats to Achievement

-0.222

-0.293 to -0.151

-0.486

-0.550 to -0.422

-0.497

-0.562 to -0.431

Resilience Domain

-0.037

-0.117 to 0.042

-0.278

-0.355 to -0.201

-0.224

-0.307 to -0.142

Family Involvement

0.003

-0.077 to 0.084

-0.190

-0.266 to -0.113

-0.181

-0.256 to -0.106

Physical Activity

0.045

-0.036 to 0.125

-0.140

-0.220 to -0.060

-0.063

-0.140 to 0.014

Social Problem Solving

-0.104

-0.187 to -0.022

-0.227

-0.309 to -0.145

-0.199

-0.293 to -0.105

Achievement Domain

-0.267

-0.336 to -0.199

-0.472

-0.539 to -0.405

-0.499

-0.565 to -0.433

Academic Performance

-0.292

-0.362 to -0.221

-0.493

-0.561 to -0.425

-0.463

-0.536 to -0.390

Peer Relations

-0.101

-0.180 to -0.022

-0.245

-0.321 to -0.169

-0.322

-0.399 to -0.244

Adolescents n = 165-181

      

Total Score

-0.175

-0.304 to -0.045

-0.510

-0.615 to -0.405

-0.499

-0.626 to -0.372

Satisfaction Domain

-0.040

-0.167 to 0.086

-0.237

-0.376 to -0.097

-0.291

-0.449 to -0.132

Satisfaction with Health

-0.040

-0.171 to 0.091

-0.157

-0.298 to -0.017

-0.191

-0.356 to -0.027

Satisfaction with Self

-0.028

-0.154 to 0.099

-0.268

-0.405 to -0.130

-0.308

-0.463 to -0.153

Comfort Domain

-0.070

-0.201 to 0.061

-0.235

-0.382 to -0.087

-0.282

-0.436 to -0.129

Physical Comfort

-0.027

-0.163 to 0.109

-0.054

-0.195 to 0.088

-0.137

-0.290 to 0.016

Emotional Comfort

-0.055

-0.192 to 0.082

-0.309

-0.451 to -0.166

-0.344

-0.479 to -0.210

Restricted Activity

-0.096

-0.248 to 0.056

-0.120

-0.260 to 0.020

-0.067

-0.223 to 0.088

Risk Avoidance Domain

-0.207

-0.333 to -0.081

-0.452

-0.583 to -0.321

-0.356

-0.486 to -0.226

Individual Risk Avoidance

-0.170

-0.293 to -0.046

-0.295

-0.449 to -0.141

-0.158

-0.307 to -0.010

Threats to Achievement

-0.197

-0.329 to -0.065

-0.483

-0.599 to -0.367

-0.364

-0.486 to -0.242

Resilience Domain

-0.109

-0.244 to 0.026

-0.305

-0.433 to -0.176

-0.318

-0.458 to -0.178

Family Involvement

0.094

-0.042 to 0.230

-0.115

-0.258 to 0.028

-0.203

-0.345 to -0.062

Physical Activity

-0.093

-0.226 to 0.040

-0.058

-0.196 to 0.081

-0.106

-0.262 to 0.051

Social Problem Solving

-0.205

-0.346 to -0.065

-0.410

-0.533 to -0.287

-0.317

-0.443 to -0.191

Achievement Domain

-0.205

-0.336 to -0.073

-0.572

-0.672 to -0.471

-0.568

-0.685 to -0.451

Academic Performance

-0.270

-0.415 to -0.125

-0.639

-0.736 to -0.543

-0.541

-0.664 to -0.418

Peer Relations

-0.073

-0.223 to 0.078

-0.284

-0.422 to -0.146

-0.334

-0.472 to -0.195

  1. Abbreviations: CHIP-CE, Child Health and Illness Profile-Child Edition; ADHD-RS, Attention Deficit/Hyperactivity Disorder Rating Scale; CI, confidence interval; r, Pearson's correlation coefficient
  2. Correlations larger than 0.3 were marked in bold to improve readability.