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Table 8 Correlation between Child Health and Illness Profile-Child Edition and ADHD-Rating Scale inattentive subscore, by age groups based on data of all 5 trials.

From: Differences between children and adolescents in treatment response to atomoxetine and the correlation between health-related quality of life and Attention Deficit/Hyperactivity Disorder core symptoms: Meta-analysis of five atomoxetine trials

CHIP-CE Baseline Endpoint Change from baseline
  R 95% CI r 95% CI r 95% CI
Children n = 570-609       
Total Score -0.275 -0.345 to -0.205 -0.513 -0.575 to -0.452 -0.535 -0.595 to -0.475
Satisfaction Domain -0.137 -0.213 to -0.060 -0.285 -0.361 to -0.209 -0.327 -0.403 to -0.252
Satisfaction with Health -0.106 -0.183 to -0.028 -0.201 -0.278 to -0.124 -0.243 -0.326 to -0.159
Satisfaction with Self -0.134 -0.210 to -0.058 -0.315 -0.390 to -0.240 -0.340 -0.412 to -0.268
Comfort Domain -0.188 -0.260 to -0.116 -0.317 -0.391 to -0.243 -0.354 -0.423 to -0.285
Physical Comfort -0.062 -0.141 to 0.016 -0.152 -0.230 to -0.073 -0.153 -0.227 to -0.079
Emotional Comfort -0.240 -0.310 to -0.169 -0.376 -0.448 to -0.305 -0.430 -0.495 to -0.365
Restricted Activity -0.068 -0.145 to 0.010 -0.095 -0.174 to -0.017 -0.078 -0.161 to 0.004
Risk Avoidance Domain -0.273 -0.343 to -0.204 -0.496 -0.562 to -0.431 -0.511 -0.576 to -0.446
Individual Risk Avoidance -0.293 -0.360 to -0.226 -0.390 -0.462 to -0.317 -0.372 -0.452 to -0.292
Threats to Achievement -0.222 -0.293 to -0.151 -0.486 -0.550 to -0.422 -0.497 -0.562 to -0.431
Resilience Domain -0.037 -0.117 to 0.042 -0.278 -0.355 to -0.201 -0.224 -0.307 to -0.142
Family Involvement 0.003 -0.077 to 0.084 -0.190 -0.266 to -0.113 -0.181 -0.256 to -0.106
Physical Activity 0.045 -0.036 to 0.125 -0.140 -0.220 to -0.060 -0.063 -0.140 to 0.014
Social Problem Solving -0.104 -0.187 to -0.022 -0.227 -0.309 to -0.145 -0.199 -0.293 to -0.105
Achievement Domain -0.267 -0.336 to -0.199 -0.472 -0.539 to -0.405 -0.499 -0.565 to -0.433
Academic Performance -0.292 -0.362 to -0.221 -0.493 -0.561 to -0.425 -0.463 -0.536 to -0.390
Peer Relations -0.101 -0.180 to -0.022 -0.245 -0.321 to -0.169 -0.322 -0.399 to -0.244
Adolescents n = 165-181       
Total Score -0.175 -0.304 to -0.045 -0.510 -0.615 to -0.405 -0.499 -0.626 to -0.372
Satisfaction Domain -0.040 -0.167 to 0.086 -0.237 -0.376 to -0.097 -0.291 -0.449 to -0.132
Satisfaction with Health -0.040 -0.171 to 0.091 -0.157 -0.298 to -0.017 -0.191 -0.356 to -0.027
Satisfaction with Self -0.028 -0.154 to 0.099 -0.268 -0.405 to -0.130 -0.308 -0.463 to -0.153
Comfort Domain -0.070 -0.201 to 0.061 -0.235 -0.382 to -0.087 -0.282 -0.436 to -0.129
Physical Comfort -0.027 -0.163 to 0.109 -0.054 -0.195 to 0.088 -0.137 -0.290 to 0.016
Emotional Comfort -0.055 -0.192 to 0.082 -0.309 -0.451 to -0.166 -0.344 -0.479 to -0.210
Restricted Activity -0.096 -0.248 to 0.056 -0.120 -0.260 to 0.020 -0.067 -0.223 to 0.088
Risk Avoidance Domain -0.207 -0.333 to -0.081 -0.452 -0.583 to -0.321 -0.356 -0.486 to -0.226
Individual Risk Avoidance -0.170 -0.293 to -0.046 -0.295 -0.449 to -0.141 -0.158 -0.307 to -0.010
Threats to Achievement -0.197 -0.329 to -0.065 -0.483 -0.599 to -0.367 -0.364 -0.486 to -0.242
Resilience Domain -0.109 -0.244 to 0.026 -0.305 -0.433 to -0.176 -0.318 -0.458 to -0.178
Family Involvement 0.094 -0.042 to 0.230 -0.115 -0.258 to 0.028 -0.203 -0.345 to -0.062
Physical Activity -0.093 -0.226 to 0.040 -0.058 -0.196 to 0.081 -0.106 -0.262 to 0.051
Social Problem Solving -0.205 -0.346 to -0.065 -0.410 -0.533 to -0.287 -0.317 -0.443 to -0.191
Achievement Domain -0.205 -0.336 to -0.073 -0.572 -0.672 to -0.471 -0.568 -0.685 to -0.451
Academic Performance -0.270 -0.415 to -0.125 -0.639 -0.736 to -0.543 -0.541 -0.664 to -0.418
Peer Relations -0.073 -0.223 to 0.078 -0.284 -0.422 to -0.146 -0.334 -0.472 to -0.195
  1. Abbreviations: CHIP-CE, Child Health and Illness Profile-Child Edition; ADHD-RS, Attention Deficit/Hyperactivity Disorder Rating Scale; CI, confidence interval; r, Pearson's correlation coefficient
  2. Correlations larger than 0.3 were marked in bold to improve readability.