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Table 9 Correlation between Child Health and Illness Profile-Child Edition and ADHD-Rating Scale hyperactive/impulsive subscore, by age groups based on data of all 5 trials.

From: Differences between children and adolescents in treatment response to atomoxetine and the correlation between health-related quality of life and Attention Deficit/Hyperactivity Disorder core symptoms: Meta-analysis of five atomoxetine trials

CHIP-CE Baseline Endpoint Change from baseline
Children n = 570-609 r 95% CI r 95% CI r 95% CI
Total Score -0.295 -0.365 to -0.224 -0.482 -0.545 to -0.419 -0.478 -0.541 to -0.414
Satisfaction Domain -0.005 -0.092 to 0.082 -0.191 -0.269 to -0.113 -0.278 -0.357 to -0.198
Satisfaction with Health 0.077 -0.013 to 0.167 -0.092 -0.171 to -0.014 -0.189 -0.275 to -0.104
Satisfaction with Self -0.093 -0.173 to -0.013 -0.261 -0.338 to -0.185 -0.305 -0.381 to -0.228
Comfort Domain -0.154 -0.232 to -0.075 -0.253 -0.328 to -0.179 -0.326 -0.394 to -0.258
Physical Comfort -0.012 -0.091 to 0.068 -0.039 -0.114 to 0.037 -0.129 -0.207 to -0.052
Emotional Comfort -0.249 -0.319 to -0.179 -0.373 -0.444 to -0.302 -0.402 -0.466 to -0.337
Restricted Activity 0.018 -0.068 to 0.105 -0.035 -0.117 to 0.046 -0.074 -0.147 to -0.000
Risk Avoidance Domain -0.524 -0.573 to -0.475 -0.613 -0.670 to -0.557 -0.522 -0.585 to -0.459
Individual Risk Avoidance -0.478 -0.530 to -0.425 -0.507 -0.571 to -0.444 -0.389 -0.468 to -0.310
Threats to Achievement -0.478 -0.531 to -0.425 -0.587 -0.643 to -0.531 -0.502 -0.566 to -0.437
Resilience Domain -0.032 -0.107 to 0.043 -0.259 -0.335 to -0.183 -0.163 -0.247 to -0.079
Family Involvement -0.026 -0.100 to 0.047 -0.179 -0.256 to -0.101 -0.128 -0.206 to -0.051
Physical Activity 0.174 0.096 to 0.252 -0.057 -0.138 to 0.024 -0.018 -0.095 to 0.058
Social Problem Solving -0.163 -0.244 to -0.082 -0.263 -0.341 to -0.184 -0.168 -0.265 to -0.070
Achievement Domain -0.196 -0.270 to -0.121 -0.412 -0.482 to -0.342 -0.413 -0.486 to -0.340
Academic Performance -0.089 -0.162 to -0.015 -0.361 -0.436 to -0.285 -0.376 -0.453 to -0.299
Peer Relations -0.210 -0.286 to -0.134 -0.295 -0.369 to -0.221 -0.287 -0.368 to -0.207
Adolescents n = 165-181       
Total Score -0.347 -0.490 to -0.203 -0.481 -0.595 to -0.368 -0.436 -0.566 to -0.306
Satisfaction Domain -0.041 -0.189 to 0.107 -0.143 -0.289 to 0.004 -0.219 -0.382 to -0.056
Satisfaction with Health 0.008 -0.141 to 0.157 -0.080 -0.228 to 0.067 -0.108 -0.267 to 0.050
Satisfaction with Self -0.078 -0.216 to 0.059 -0.178 -0.322 to -0.034 -0.269 -0.422 to -0.115
Comfort Domain -0.208 -0.349 to -0.067 -0.297 -0.429 to -0.166 -0.286 -0.428 to -0.144
Physical Comfort -0.049 -0.177 to 0.080 -0.064 -0.213 to 0.085 -0.129 -0.273 to 0.016
Emotional Comfort -0.302 -0.441 to -0.164 -0.426 -0.540 to -0.312 -0.371 -0.496 to -0.246
Restricted Activity -0.005 -0.144 to 0.135 -0.079 -0.228 to 0.069 -0.049 -0.209 to 0.110
Risk Avoidance Domain -0.568 -0.671 to -0.466 -0.593 -0.701 to -0.485 -0.359 -0.492 to -0.226
Individual Risk Avoidance -0.474 -0.596 to -0.352 -0.484 -0.621 to -0.347 -0.181 -0.328 to -0.035
Threats to Achievement -0.531 -0.633 to -0.430 -0.570 -0.673 to -0.468 -0.345 -0.476 to -0.215
Resilience Domain -0.181 -0.322 to -0.040 -0.235 -0.370 to -0.100 -0.294 -0.432 to -0.156
Family Involvement -0.085 -0.215 to 0.046 -0.198 -0.324 to -0.072 -0.181 -0.328 to -0.035
Physical Activity 0.091 -0.051 to 0.233 0.059 -0.083 to 0.201 -0.071 -0.210 to 0.068
Social Problem Solving -0.292 -0.422 to -0.161 -0.311 -0.454 to -0.168 -0.309 -0.434 to -0.185
Achievement Domain -0.233 -0.377 to -0.089 -0.472 -0.583 to -0.362 -0.471 -0.595 to -0.347
Academic Performance -0.097 -0.244 to 0.050 -0.495 -0.603 to -0.388 -0.421 -0.557 to -0.284
Peer Relations -0.244 -0.383 to -0.104 -0.264 -0.406 to -0.123 -0.282 -0.410 to -0.154
  1. Abbreviations: CHIP-CE, Child Health and Illness Profile-Child Edition; ADHD-RS, Attention Deficit/Hyperactivity Disorder Rating Scale; CI, confidence interval; r, Pearson's correlation coefficient
  2. Correlations larger than 0.3 were marked in bold to improve readability.