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Table 2 Comparison of mean (SD) scores at baseline, Week 4 and Week 8

From: Risperidone in the treatment of conduct disorder in preschool children without intellectual disability

Scale

Subscale

Rater

Baseline* Mean(SD)

4 th week Mean(SD)

8 th week Mean(SD)

F

Pairwise comparisons

T-DSM-IV-S

IA

P

16.1(6.3)

9.6(4.1)

8.5(3.6)

6.129

8th < Baseline(p = 0.021)

  

C

18.9(5.1)

13.9(1.8)

10.1(2.1)

22.561

4th < Baseline(p = 0.08)

8th < Baseline(p = 0.01)

8th < 4th(p = 0.01)

T-DSM-IV-S

H-I

P

22.6(4.5)

13.0(5.4)

11.0(3.3)

17.452

4th < Baseline(p = 0.07)

8th < Baseline(p < 0.001)

  

C

21.6(2.8)

12.8(4.2)

9.6(2.8)

23.098

4th < Baseline(p = 0.004)

8th < Baseline(p < 0.001)

T-DSM-IV-S

OD

P

16.9(5.4)

10.9(6.2)

8.3(2.9)

11.818

4th < Baseline(p = 0.039)

8th < Baseline(p < 0.001)

  

C

17.4(2.8)

11.4(2.8)

7.1(1.4)

33.126

4th < Baseline(p = 0.001)

8th < Baseline(p < 0.001)

8th < 4th(p = 0.017)

T-DSM-IV-S

CD

P

14.0(8.6)

5.1(4.9)

4.0(2.1)

8.924

4th < Baseline(p = 0.033)

8th < Baseline(p = 0.007)

  

C

14.0(4.8)

7.4(2.9)

4.5(2.4)

16.119

4th < Baseline(p = 0.012)

8th < Baseline(p = 0.001)

T-DSM-IV-S

Total

P

69.5(19.1)

38.9(19.1)

31.8(8.8)

13.393

4th < Baseline(p = 0.020)

8th < Baseline(p = 0.001)

  

C

71.9(12.7)

46.9(11.1)

31.0(5.6)

30.410

4th < Baseline(p = 0.003)

8th < Baseline(p < 0.001)

8th < 4th(p = 0.015)

CGI

Severity

C

6.4(0.5)

1.8(1.0)

1.4(0.5)

165.444

4th &8th < Baseline (p < 0.001)

CGI

Improvement

C

2.5(0.5)

1.8(0.7)

1.4(0.5)

6.785

4th > Baseline(p = 0.048)

8th > Baseline(p = 0.002)

  1. T-DSM-IV-S: Turgay DSM-IV Based Child and Adolescent Behavior Disorders Screening and Rating Scale; CGI: Clinical Global Impression Scale; IA: Inattention; H-I: Hyperactivity-Impulsivity; OD: Opposition-Defiance; CD: Conduct Disorder; P: Parent; C: Clinician
  2. *For CGI-Improvement Subscale assessments, 2nd week was accepted as baseline