Table 4 Response Probabilities Over Time
Endpoint | Probability That Endpoint Was Observed at or Before: | Expected Week by Which This Percentage of Study Participants Will Have Achieved Endpoint: | |||||
|---|---|---|---|---|---|---|---|
4 weeks | 12 weeks | 26 weeks | 52 weeks | 25% | 50% | 75% | |
Improvement | 0.60 (0.38, 0.79) | 0.88 (0.75, 0.95) | 0.96 (0.85, 0.99) | 1.00 | -- | 3.7 | 7.2 |
Robust Improvement | 0.47 (0.30, 0.65) | 0.76 (0.60, 0.87) | 0.85 (0.67, 0.94) | 0.96 (0.87, 0.99) | 3.6 | 4.7 | 12.0 |
Remission* | 0.30 (0.16, 0.49) | 0.59 (0.34, 0.79) | 0.77 (0.48, 0.92) | 0.85 (0.72, 0.93) | 3.7 | 8.0 | 23.8 |
Remission** | 0.08 (0.04, 0.16) | 0.47 (0.26, 0.70) | 0.67 (0.51, 0.80) | 0.75 (0.60, 0.85) | 5.3 | 14.3 | 52.3 |