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Table 1 Demographic data and disease characteristics (by age group).

From: Improved functionality, health related quality of life and decreased burden of disease in patients with ADHD treated with OROS® MPH: is treatment response different between children and adolescents?

Age 6-12 years N = 583 13-18 years N = 239 All patients N = 822 U-test1 Chi2-test2
Gender, n (%)     p = 0.4602
   Female 84 (14.41) 40 (16.74) 124 (15.09)  
   Male 499 (85.59) 199 (83.26) 698 (84.91)  
Age at study start (years)     
   mean ± SD 9.75 ± 1.59 14.38 ± 1.29 11.10 ± 2.58 p < 0.0011
   minimum, median, maximum 6,10,12 13,14,18 6,11,18  
Age at study start (years) by group, n (%)     
   6-9 251 (43.05) 0 (0.00) 251 (30.54)  
   10-12 332 (56.95) 0 (0.00) 332 (40.39)  
   13-15 0 (0.00) 197 (82.43) 197 (23.97)  
   16-18 0 (0.00) 42 (17.57) 42 (5.11)  
Age at first diagnosis of disease (years)     p < 0.0011
   valid N 565 220 785  
   mean ± SD 7.31 ± 1.85 9.97 ± 2.86 8.06 ± 2.49  
   minimum, median, maximum 2,7,12 1.0,10.0,16.0 1.0,8.0,16.0  
Duration of disease at study start (years)     p < 0.0011
   valid N 565 220 785  
   mean ± SD 2.41 ± 1.56 4.27 ± 2.71 2.93 ± 2.12  
   minimum, median, maximum 0.03,2.1,7.9 0.17,3.8,12 0.03,2.51, 12  
Diagnosis of ADHD (ICD-10) n (%)3     
   F90.0: disturbance of activity and attention 364 (62.44) 155 (64.85) 519 (63.14) p = 0.5672
   F90.1: hyperkinetic conduct disorder 227 (38.94) 89 (37.24) 316 (38.44) p = 0.7072
   F90.8: other hyperkinetic disorder 8 (1.37) 6 (2.51) 14 (1.70) p = 0.3962
   F90.9: hyperkinetic disorder, unspecified 18 (3.09) 3 (1.26) 21 (2.55) p = 0.2052
   others 41 (7.03) 24 (10.04) 65 (7.91) p = 0.2872
Previous and/or concomitant diseases (ICD-10) n (%)3     
   No 351 (60.21) 145 (60.67) 496 (60.34) p = 0.9642
   Others 47 (8.06) 26 (10.87) 73 (8.88)  
   F91.X: conduct disorder 134 (22.98) 53 (22.18) 187 (22.75) p = 0.2882
   F91: incl. F91.3 oppositional defiant disorder 103 (17.67) 37 (15.48) 140 (17.03) p = 0.5122
   F41: anxiety disorder 25 (4.29) 7 (2.93) 32 (3.89) p = 0.5342
   F42: obsessive-compulsive disorder 12 (2.06) 3 (1.26) 15 (1.82) p = 0.5992
   F1X: substance abuse 0 (0.00) 6 (2.51) 6 (0.73) p = 0.0012
  1. 1,2 p-values from the corresponding test between age groups: 6-12 years and 13-18 years
  2. 3 multiple responses possible; Chi2-test always yes vs. no