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Table 1 Baseline Demographic and Clinical Characteristics of Randomized Participants Classified as Nonremitters During Prior MPH Treatment

From: Efficacy of lisdexamfetamine dimesylate in children with attention-deficit/hyperactivity disorder previously treated with methylphenidate: a post hoc analysis

Participant

Age (years)

Sex

Weight (kg)

Medication

Total Daily Dose (mg/day)

Average Daily Dose (mg/kg)

Screening ADHD-RS-IV Total Score

1

6

F

22.68

OROS MPH*

≥ 30

≥ 1.0

50

2

7

M

29.48

ER MPH

20

< 1.0

20

3

7

F

44.45

OROS MPH

36

< 1.0

28

4

8

M

44.36

OROS MPH

18

< 1.0

38

5

8

M

26.31

OROS MPH

54

≥ 1.0

38

6

8

M

33.57

OROS MPH;

IR dMPH

54;

2.5

≥ 1.0

50

7

8

M

41.28

OROS MPH

18

< 1.0

43

8

8

F

43.68

IR MPH

30

< 1.0

50

9

9

M

29.03

ER MPH

20

< 1.0

29

10

9

M

26.76

OROS MPH

54

≥ 1.0

39

11

9

M

31.75

MPH CD

40

≥ 1.0

29

12

9

M

26.31

OROS MPH

27

≥ 1.0

45

13

9

F

28.12

SR MPH

20

< 1.0

40

14

9

F

25.18

IR MPH*

≥ 50

≥ 1.0

34

15

9

F

24.90

OROS MPH

27

≥ 1.0

20

16

10

M

39.01

OROS MPH

54

≥ 1.0

23

17

10

F

43.68

OROS MPH†

36

< 1.0

22

18

10

F

27.67

OROS MPH

54

≥ 1.0

37

19

10

F

29.03

IR MPH

50

≥ 1.0

44

20

11

M

45.36

OROS MPH

72

≥ 1.0

35

21

11

M

45.36

OROS MPH

36

< 1.0

41

22

12

M

39.46

OROS MPH

54

≥ 1.0

45

23

12

M

34.02

OROS MPH

18

< 1.0

45

24

12

M

33.57

OROS MPH

54

≥ 1.0

44

25

12

F

34.02

OROS MPH

36

≥ 1.0

51

26

12

F

26.76

OROS MPH

54

≥ 1.0

25

  1. ADHD-RS-IV = Attention-Deficit/Hyperactivity Disorder Rating Scale IV; dMPH = dexmethylphenidate; ER = extended-release; IR = immediate-release; MPH = methylphenidate; CD = controlled delivery; OROS = osmotic-release oral system; SR = sustained-release.
  2. *Exact dose of treatment for these participants could not be determined; †Participant was also receiving 40 mg/d of IR mixed amphetamine salts although this was not included in the calculation of MPH dose.