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Table 2 Characteristics of participating CH patients and their parents

From: Health- related quality of life and self-worth in 10-year old children with congenital hypothyroidism diagnosed by neonatal screening

PATIENTS

Severe CH

Moderate/Mild CH

 

Number of patients (male/female)

41 (13/28)

41 (16/25)

 

Initial FT4

   

in ng/dl (95%CI)*

0.1 (0.0-0.3)

0.7 (0.3-1.1)

 

[in nmol/l (95%CI)]

[1.8 (0.0-4.0)]

[9.4 (4.2-20.2]

 

Age at start of T4 supplementation in mean days (range)

19 (10–43)

25 (2–73)

 

Mean IQ scores at 10.5 yr **

Severe

Moderate

Mild

  Full scale IQ

93.7 (89.5-97.9)

96.2 (88.9-103.5)

105.0 (99.5-110.4)

  Verbal IQ

94.9 (90.1-99.7)

95.4 (87.9-102.9)

103.6 (98.2-109.1)

  Performance IQ

93.9 (90.0-97.8)

98.0 (91.1-104.9)

105.3 (99.3-111.3)

Mean motor scores at 10.5 yr **

   

Total MABC score***

14.3 (11.8-16.8)

9.7 (6.8-12.5)

11.6 (8.7-14.6)

PARENTS

   

Number of the participating parents (mothers/fathers)

35 (26/9)

38 (33/5)

 

Parental marital status

   

Married/living together, n (%)

32 (91)

37 (97)

 

Single, n (%)

3 (9)

1 (3)

 

Educational level father

   

 Low, n (%)

11 (31)

18 (47)

 

 Middle, n (%)

11 (31)

11 (29)

 

 High, n (%)

13 (38)

9 (24)

 

Educational level father

   

 Low, n (%)

17 (47)

18 (47)

 

 Middle, n (%)

12 (34)

12 (30)

 

 High, n (%)

7 (19)

8 (23)

 
  1. * Reference range for FT4 in children aged 2–6 wk is 0.9-2.2 ng/dlL (12–28 pmol/l) (34).
  2. ** published in Kempers et al. (3).
  3. *** No motor problems: (Total MABC score ≤ 9.5), borderline motor problems : (9.5 < Total MABC score < 13.5, definite motor problems: (Total MABC score ≥ 13.5).