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Table 2 Characteristics of participating CH patients and their parents

From: Health- related quality of life and self-worth in 10-year old children with congenital hypothyroidism diagnosed by neonatal screening

PATIENTS Severe CH Moderate/Mild CH  
Number of patients (male/female) 41 (13/28) 41 (16/25)  
Initial FT4    
in ng/dl (95%CI)* 0.1 (0.0-0.3) 0.7 (0.3-1.1)  
[in nmol/l (95%CI)] [1.8 (0.0-4.0)] [9.4 (4.2-20.2]  
Age at start of T4 supplementation in mean days (range) 19 (10–43) 25 (2–73)  
Mean IQ scores at 10.5 yr ** Severe Moderate Mild
  Full scale IQ 93.7 (89.5-97.9) 96.2 (88.9-103.5) 105.0 (99.5-110.4)
  Verbal IQ 94.9 (90.1-99.7) 95.4 (87.9-102.9) 103.6 (98.2-109.1)
  Performance IQ 93.9 (90.0-97.8) 98.0 (91.1-104.9) 105.3 (99.3-111.3)
Mean motor scores at 10.5 yr **    
Total MABC score*** 14.3 (11.8-16.8) 9.7 (6.8-12.5) 11.6 (8.7-14.6)
PARENTS    
Number of the participating parents (mothers/fathers) 35 (26/9) 38 (33/5)  
Parental marital status    
Married/living together, n (%) 32 (91) 37 (97)  
Single, n (%) 3 (9) 1 (3)  
Educational level father    
 Low, n (%) 11 (31) 18 (47)  
 Middle, n (%) 11 (31) 11 (29)  
 High, n (%) 13 (38) 9 (24)  
Educational level father    
 Low, n (%) 17 (47) 18 (47)  
 Middle, n (%) 12 (34) 12 (30)  
 High, n (%) 7 (19) 8 (23)  
  1. * Reference range for FT4 in children aged 2–6 wk is 0.9-2.2 ng/dlL (12–28 pmol/l) (34).
  2. ** published in Kempers et al. (3).
  3. *** No motor problems: (Total MABC score ≤ 9.5), borderline motor problems : (9.5 < Total MABC score < 13.5, definite motor problems: (Total MABC score ≥ 13.5).