Figure 1

Translational Developmental Neuroscience. depicts the time course of atypical versus typical development. The red arrow at in early childhood indicates a perturbation followed by an immediate or later onset trajectory deviation involving dynamic changes in molecular systems, information processes running on hierarchically distributed neural networks, and resulting psychopathology, which when sufficiently altered (brown circle) comes to clinical attention. Opportunities for preemption predate the onset of clinical illness either before or early in the prodromal period of delayed development.