Fig. 1

Changes in KINDL-R patient scale from baseline to endpoint relative to the normative data for adolescent males and adolescent females [32]. The upper and lower edge of each box represents the ‘mean plus one standard deviation’, and the ‘mean minus one standard deviation’ respectively, the lines above and below each box represent the ‘mean plus two standard deviations’, and the ‘mean minus two standard deviations’ respectively. The line across the middle of each box represents the mean. KINDL-R KINDL questionnaire for measuring health-related quality of life in children and adolescents, OFC olanzapine/fluoxetine combination, PBO placebo