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Table 1 Summary of study characteristics

From: A systematic review of telehealth screening, assessment, and diagnosis of autism spectrum disorder

 

Device

Author (year)

Country

Website

Affiliation

Method

Technology utilized

Diagnosis or screening?

Observed metrics

Assess scenario

1

Cognoa

Kanne et al. [20]

US

https://cognoa.com/

Cognoa Inc

Store-and-forward method

Application

Screening

Caregiver questionnaire (MARA) + health care questionnaire + video coding (behavior features)

3 home videos shoot by their parents, and automatically coding the video

Abbas et al. [1]

US

Abbas et al. [2]

US

Megerian et al. [28, 29]

US

2

Autism & Beyond

Egger et al. [15]

US

https://autismandbeyond.com.au

Duke University

Store-and-forward method

Application

Screening

3 surveys (family background, parental concerns, and temper tantrums) + video coding (face landmark)

Watch short videos and iphones’ camera recording their face, and automatically coding the features

Campbell et al. [6]

US

Carpenter et al. [8]

US

Perochon et al. [33]

US

3

ASDTests

Thabtah et al. [45]

New Zealand

https://www.asdtests.com

Dr. Fadi Fayez in Manukau Institute of Technology

Static scoring

Application

Screening

AQ-Adult-10, AQ-Adolescent-10, AQ-Child-10, and Q-CHAT-10

Parents, care givers, and academic researchers to fill out tests, which are behavioural tests that just pinpoint to autistic traits

4

ASDetect

Barbaro and Dissanayake [5]

Australia

https://asdetect.org

Sadka et al. in Trobe University, Australia

Static scoring

Application

Screening

Questions contain self-developed early markers of ASD behavioral characteristics

Parents watch instruction videos and answer questions

5

AutismAI

Shahamiri and Thabtah [40]

New Zealand

https://www.autismai.com

Seyed Reza Shahamiri and Fadi Thabtah

Machine learning

Application

Screening

AQ and Q-CHAT-10

Users need to answer all the questions and press the submit button and generate a report

6

NA

Wingfield et al. [48]

UK

NA

NA

Machine learning

Application

Screening

The PAAS checklist (pictorial autism assessment schedule)

Users answer questions

7

TEDI

Talbott et al. [44]

US

https://health.ucdavis.edu/mindinstitute/research/telehealth-evaluation-development-for-infants/index.html#:~:text=The%20goal%20of%20the%20TEDI%20study%20is%20to,to%20a%20clinic%20to%20get%20a%20developmental%20evaluation

University of California, Davis

Real-time method

Video conferencing

Screening

AOSI + IGDI-ECI

The TEDI kit includes cue cards and toys to support 10 different interactive “scenarios,” 5 scenarios for specific items from the AOSI, and 5 additional scenarios to stimulate object exploration, play, and communication

8

CHICA

Downs et al. [14]

US

https://medicine.iu.edu/pediatrics/specialties/health-services/child-health-informatics-research-development-lab/the-chica-system

Researchers from the Regenstrief Institute and Indiana University

Static scoring

An automated system

Screening

20 questions + M-CHAT-F

Users answer 20 yes or no questions covering a wide range of primary care issues, 6 questions were selected to alert clinician

9

The video-referenced Infant Rating System for Autism (VIRSA)

Young et al. [49]

UK

NA

University of California, Davis

Machine learning

Application

Screening

Questions contains different level of social communication

The user refers to the videos on both sides of the screen (left and right) and chooses the one that most resembles the child, scoring it on a 10-point scale. The video library includes 268 videos all from 11 children with autism, 23 with non-autism, and 29 with typical development

10

Lena

Oller et al. [32]

US

https://www.lena.org

Infoture Inc

Store-and-forward method

A wearable device

Screening

Assess children’s language development + M-CHAT

The parent or teacher places the LENA device in the child’s LENA undershirt and records the child’s sound environment throughout the day. The device then processes the recordings into data indicators connected to a computer, including the child’s exposure to speech stimuli, the amount of speech the child speaks, and other information

11

SORF

Dow et al. [12]

US

NA

Florida State University

Store-and-forward method

Application

Screening

SORF coding

A videographer is present to record the observation of parent and children, and the parents are given written and verbal instruction to interact with children. The recorded video then coded by trained coders using SORF

12

NODA

Smith et al. [41]

US

https://www.nodaautismdiagnosis.com/

Behavior Imaging Solutions Inc

Store-and-forward method

Application

Diagnosis

DSM-5

NODA consists of 2 components: (1) NODACapture, an app to allow parents to record video evidence of their child’s prescribed behavior at home; and (2) NODA Connect, a web portal that enables physicians to assess the child based on home video and developmental history and by linking evidence of behavior flagged in the video to DSM5 criteria

13

NA

Reese et al. [37]

US

NA

Interdisciplinary Technical Assistance Center on Autism and Developmental Disabilities, University of Kansas

Real-time method

Video conference

Diagnosis

DSM-5 + ADI-R + ADOS-2

Video conference to evaluate ASD

14

NA

Juárez et al. [19]

US

NA

NA

Real-time method

Fixed point-tilt-zoom cameras in clinic rooms/ video conference

diagnosis

STAT + DSM-5 + clinical best estimate (CBE) + MSEL + VABSII + ADOS-2

Use camera or video conference to remote diagnosis

15

The Brief Observation of Symptoms of Autism (BOSA)

[13]

US

https://www.sfari.org/funded-project/the-initial-standardization-of-the-brief-observation-of-symptoms-of-autism-bosa/

Funded by Simons Foundation, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles (UCLA)

Real-time method

Video conferencing

Diagnosis

Four versions of BOSA (PSYF, MV, F1, F2)

A 12–14 min interaction between an individual and a caregiver or clinician, materials are picked based on age and language and developmental level, and a trained clinician observe and code base on the BOSA manual

16

TeleNP

Ransom et al. [36]

US

https://www.teladochealth.com

Teladoc Health Inc

Real-time method

A video-based practice model

Screening and diagnosis

DSM-5 + CARS-2 + NEPSY-II + DKEFS + Vineland-3 + ADOS-2

Verbal instructions were provided to families by telephone to set environment, 20- to 30-min child interview and observation online, different assessments conducted via teleNP

Salinas et al. [39]

US

17

The TELE-ASD-PEDS

Stavropoulos et al. [42, 43]

US

https://triad.vkclearning.org/

Vanderbilt Kennedy Center: Treatment and Research Institute for Autism Spectrum Disorders (TRIAD)

Real-time method

Video conferencing

Assessment

ADOS-2 (Modules 2 and 3)

Module 2 (15 Activities and 9 codes), module 3 (11 Activities and 10 codes)

Corona et al. [10]

US

Wagner et al. [47]

US

  1. AQ The Autism-Spectrum Quotient Test, Q-CHAT The Quantitative Checklist for Autism in Toddlers, PAAS Checklist Pictorial Autism Assessment Schedule checklist, AOSI The Autism Observation Scale for Infants, IGDI Individual Growth and Development Indicators, ECI Early Childhood Intervention, M-CHAT The Modified Checklist for Autism in Toddlers, ADI-R The Autism Diagnostic Interview-Revised, ADOS-2 The Autism Diagnostic Observation Schedule, Second Edition, STAT Screening Tool for Autism in Toddlers & Young Children, CBE clinical best estimate, MSEL Mullen Scales of Early Learning, VABSII Vineland Adaptive Behavior Scale, CARS-2 Childhood Autism Rating Scale, Second Edition, NEPSY-II NEPSY-Second Edition, DKEFS Delis–Kaplan Executive Function System, Vineland-3 The Vineland Adaptive Behaviour Scales, Third Edition, ESAC the Early Screening for Autism and Communication Disorders, MSEL Mullen Scales of Early Learning, VABS-2 Vineland Adaptive Behavior Scale-Second Edition