Male-specific, replicable and functional roles of genetic variants and cerebral gray matter volumes in ADHD: a gene-wide association study across KTN1 and a region-wide functional validation across brain

Table 2 p values for rs10132888-ADHD (in males) and -mRNA associations

"SNP-ADHD" association			"SNP-mRNA" association (Europeans)
Risk allele	Discovery sample (ABCD)	Replication sample (PUWMa)	Effective allele	GTEx	BRAINEAC	GTEx	GTEx	GTEx	GTEx
				Cortex	Limbic system		BG	Cerebellum
				Frontal	Thalamus	Hippocampus	NAc	CRBL	CRBH
A	0.041	0.007	G	0.003	4.8 × 10^–4	0.007	1.2 × 10^–5	0.003	0.032

Risk allele is a major allele (f > 0.5)
BG, Basal ganglia; NAc, Nucleus accumbens; CRBL, Cerebellar cortex; CRBH, Cerebellar hemisphere

ISSN: 1753-2000