Fig. 1From: Individual brain regulation as learned via neurofeedback is related to affective changes in adolescents with autism spectrum disorderResults of the resting brain activity and brain regulation task analyses. The increase in the percent amplitude of fluctuations (PerAF) of the anterior cingulate cortex over both, the slow cortical potentials (SCP) neurofeedback and treatment as usual (TAU) group, is visualized in the top-left diagram. The middle-left diagram shows a PerAF increase in the precentral gyrus of the TAU and generally higher values in the SCP group. The bottom-left plot shows the PerAF changes over both groups in the temporal gyrus with stronger increases in the TAU group. The right scatter plots show the correlation of the brain regulation task (Pearson’s r corresponding to the parametric analysis as implemented in Statistical Parametric Mapping and Spearman’s due to potential outliers): The difference between the “Up” and “Down” conditions (i.e., fMRI differentiation) was anticorrelated with changes on the Lability/Negativity (ERC ΔLN) subscale of the Emotion Regulation Checklist. The SCP positivity condition correlated with changes on the Emotion Regulation (ERC ΔER) subscale. Changes on the Griffith Empathy Measure Cognitive Empathy (GEM ΔCE) subscale again significantly correlated with fMRI differentiation. The whole-brain 3D models were created using BrainNet Viewer 1.7 [73]Back to article page