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Table 1 Baseline characteristics

From: Individual brain regulation as learned via neurofeedback is related to affective changes in adolescents with autism spectrum disorder

Score

Neurofeedback

Treatment as usual

N

21

20

Age1 [years]

14.44 ± 1.90

15.01 ± 1.59

IQ: WISC/WAIS2

100.82 ± 17.34

101.57 ± 14.14

IQ: qualitative3 [median]

average

average

ADI-R4: social interaction

12.25 ± 4.90

17.00 ± 7.73

ADI-R4: communication and language

10.08 ± 6.17

13.65 ± 5.40

ADI-R4: restricted and repetitive behavior

3.67 ± 2.71

3.75 ± 1.23

SRS: total

99.57 ± 26.10

89.50 ± 25.94

SRS: social awareness

12.57 ± 3.22

11.45 ± 4.01

SRS: social cognition

18.38 ± 4.90

15.50 ± 6.01

SRS: social communication

34.95 ± 11.14

30.70 ± 9.32

SRS: social motivation

15.86 ± 5.92

16.25 ± 5.18

SRS: autistic mannerism

17.81 ± 6.59

15.60 ± 6.29

SCQ: total

18.62 ± 7.26

15.10 ± 6.88

SCQ: social interaction

7.05 ± 4.02

5.60 ± 3.76

SCQ: communication

6.86 ± 2.57

6.10 ± 3.09

SCQ: stereotyped behavior

4.52 ± 2.42

3.10 ± 2.47

ASD subtype: deficits in social interaction5 [n]

5

6

ASD subtype: repetitive behavior and interests5 [n]

1

2

ASD subtype: deficits in social interaction + repetitive behavior and interests5 [n]

12

10

ASD subtype: deficits in social interaction + deficits in language5 [n]

1

1

ASD subtype: deficits in social interaction + deficit in language + repetitive behavior and interests5 [n]

2

1

DISYPS-II: ADHD total6 [standard nine]

7.5 ± 0.98

7.10 ± 1.17

DISYPS-II: attention deficits [standard nine]

7.33 ± 1.29

7.20 ± 1.15

DISYPS-II: hyperactivity [standard nine]

6.38 ± 1.77

5.55 ± 2.98

DISYPS-II: impulsivity [standard nine]

7.76 ± 1.09

5.90 ± 3.65

DISYPS-II: competences [standard nine]

3.90 ± 1.55

3.20 ± 1.91

  1. Unless otherwise specified, scores are given as mean ± standard deviation
  2. WISC/WAIS: Wechsler Intelligence Scale for Children/Wechsler Adult Intelligence Scale, ADI-R: Autism Diagnostic Interview—Revised, SRS: Social Responsiveness Scale, SCQ: Social Communication Questionnaire, ASD: Autism Spectrum Disorder, DISYPS-II: Diagnostic Dystem for Psychiatric Disease in Children and Adolescent, parent-rated version 2, ADHD: attention-deficit/hyperactivity disorder
  3. 1 At first magnetic resonance imaging session
  4. 2 WISC/WAIS IQs were available for 11 participants in the neurofeedback and 14 in the treatment as usual group. Two participants in the neurofeedback group had an IQ of 96 and 120, respectively, assessed via the Adaptive Intelligence Diagnostic, version 2
  5. 3 Only one participant in the treatment as usual group was rated “slightly above average”, none below
  6. 4 Available for 12 participants in the neurofeedback and ten participants in the treatment as usual group
  7. 5 Clinical observer assessment; no “deficits in language”-only subtype was observed in any group
  8. 6 Combines the “attention deficits”, “hyperactivity” and “impulsivity” subscales