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Table 4 Child Health and Illness Profile-Child Edition, baseline data

From: Differences between children and adolescents in treatment response to atomoxetine and the correlation between health-related quality of life and Attention Deficit/Hyperactivity Disorder core symptoms: Meta-analysis of five atomoxetine trials

 

Placebo controlled studies

All studies

CHIP-CE items

Children

(N = 275)

Adolescents

(N = 112)

p-value

Children

(N = 611)

Adolescents

(N = 183)

p-value

CHIP-CE

      

   Total Score

31.9 (10.87)

29.3 (11.80)

0.030

29.3 (11.58)

27.5 (12.29)

0.296

   Satisfaction Domain

36.3 (13.66)

32.9 (14.20)

0.031

34.9 (13.88)

32.9 (14.49)

0.066

   Satisfaction with Health

43.0 (12.89)

40.8 (14.13)

0.294

40.9 (13.22)

40.6 (14.45)

0.388

   Satisfaction with Self

32.4 (13.99)

28.6 (13.88)

0.004

32.3 (14.34)

29.0 (14.21)

0.018

   Comfort Domain

46.0 (9.92)

46.2 (10.35)

0.526

43.3 (10.75)

44.7 (11.00)

0.426

   Physical Comfort

52.0 (9.32)

52.7 (9.80)

0.423

50.7 (9.84)

52.0 (10.18)

0.850

   Emotional Comfort

41.0 (10.96)

42.0 (10.76)

0.162

37.7 (11.80)

39.9 (11.59)

0.029

   Restricted Activity

50.5 (10.13)

47.4 (11.07)

0.022

50.2 (10.02)

48.1 (10.89)

0.027

   Risk Avoidance Domain

33.7 (12.11)

32.8 (12.54)

0.396

30.6 (14.75)

29.0 (14.18)

0.378

   Individual Risk Avoidance

39.1 (13.15)

40.9 (12.83)

0.213

35.6 (15.71)

35.8 (15.28)

0.004

   Threats to Achievement

33.8 (11.80)

31.8 (12.39)

0.064

31.4 (13.67)

29.2 (13.27)

0.719

   Resilience Domain

36.2 (11.98)

35.2 (11.20)

0.197

36.5 (11.91)

34.5 (12.33)

0.096

   Family Involvement

40.6 (10.84)

36.7 (10.74)

<0.001

41.4 (11.26)

36.3 (12.24)

<0.001

   Physical Activity

44.4 (11.20)

45.2 (11.04)

0.952

46.4 (11.73)

46.5 (11.94)

0.373

   Social Problem Solving

36.9 (12.58)

38.2 (12.36)

0.452

35.1 (13.01)

35.8 (12.85)

0.112

   Achievement Domain

33.4 (9.92)

29.2 (10.50)

<0.001

31.0 (10.26)

28.9 (10.71)

0.046

   Academic Performance

32.8 (9.47)

27.9 (8.80)

<0.001

32.0 (9.91)

27.7 (9.38)

<0.001

   Peer Relations

39.7 (13.35)

38.6 (14.40)

0.703

36.7 (13.19)

38.4 (14.12)

0.051

  1. Data is presented as unadjusted mean and SD (if not otherwise indicated)
  2. p-value is based on two-way analysis of variance (ANOVA) including terms age and study
  3. Abbreviations: CHIP-CE, Child Health and Illness Profile, Child Edition; SD, standard deviation
  4. Significant p-values are bolded
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Child and Adolescent Psychiatry and Mental Health

ISSN: 1753-2000