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Table 1 Baseline demographic and clinical characteristics of adolescents with schizophrenia

From: An open-label, multicenter evaluation of the long-term safety and efficacy of risperidone in adolescents with schizophrenia

Parameter

PBO/RIS

RIS/RIS

Direct-enroll

All subjects

(n = 48)

(n = 292)

(n = 50)

(N = 390)

Age, mean (SD), y

15.4 (1.4)

15.5 (1.7)

15.5 (1.4)

15.5 (1.6)

Sex, n (%)

    

Female

18 (38)

114 (39)

20 (40)

152 (39)

Male

30 (63)

178 (61)

30 (60)

238 (61)

Weight, mean (SD), kg

59.2 (20.9)

60.3 (13.4)

67.3 (14.2)

61.0 (14.8)

Body mass index, mean (SD), kg/m2

21.8 (5.9)

21.5 (3.6)

22.5 (4.0)

21.7 (4.0)

Maximum Tanner stage, n (%)

    

1

0

6 (2)

0

6 (2)

2

3 (6)

2 (1)

1 (2)

6 (2)

3

11 (23)

32 (11)

2 (4)

45 (12)

4

21 (45)

112 (42)

26 (52)

169 (44)

5

12 (26)

128 (44)

21 (42)

161 (42)

Race, n (%)

    

White

25 (52)

218 (75)

42 (84)

285 (73)

Black or African American

4 (8)

39 (13)

8 (16)

51 (13)

Asian

19 (40)

31 (11)

0

50 (13)

Mixed

0

2 (1)

0

2 (1)

American Indian/Native Alaskan

0

1 (<1)

0

1 (<1)

Axis diagnosis, n (%)

    

Schizophrenia

48 (100)

288 (99)

50 (100)

386 (99)

Schizophreniform disorder

0

4 (1)

0

4 (1)

Diagnosis, n (%)

    

Paranoid

33 (69)

195 (67)

35 (70)

263 (67)

Undifferentiated

11 (23)

55 (19)

13 (26)

79 (20)

Disorganized

3 (6)

26 (9)

2 (4)

31 (8)

Residual

1 (2)

6 (2)

0

7 (2)

Catatonic

0

6 (2)

0

6 (2)

Schizophreniform disorder

0

4 (1)

0

4 (1)

Age at diagnosis, mean (SD), y

14.8 (1.6)

14.9 (2.2)

15.1 (1.9)

14.9 (2.1)

Age at first psychotic symptoms, mean (SD), y

12.6 (3.1)

13.4 (2.9)

13.6 (2.5)

13.3 (2.9)

Age at start of antipsychotic treatment, mean (SD), y

13.9 (2.6)

14.6 (2.3)

14.8 (1.9)

14.5 (2.3)

Time since onset of first psychotic symptoms, mean (SD), y

2.8 (2.4)

2.1 (2.3)

1.9 (2.0)

2.1 (2.3)