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Table 5 Percentage at risk for impaired health related quality of life (TACQoL): patients with congenital hypothyroidism (CH) versus the norm population

From: Health- related quality of life and self-worth in 10-year old children with congenital hypothyroidism diagnosed by neonatal screening

  Total CH Severe CH Moderate/Mild CH Norm population
Child-report     
  n = 82 n = 41 n = 41 n = 449
Physical Functioning 40% 46% * 34% 25%
Motor Functioning 48% ** 50% * 46% * 25%
Autonomy 38% ** 46% ** 29% 25%
Cognitive functioning 40% * 57% ** 25% 25%
Social Functioning 34% 41% 28% 25%
Positive emotions 45% * 42% 47% * 25%
Negative emotions 30% 36% 25% 25%
Parent-report     
  n = 82 n = 41 n = 41 n = 465
Physical Functioning 34% 37% 32% 25%
Motor Functioning 55% ** 61% ** 49%* 25%
Autonomy 27% 32% 22% 25%
Cognitive functioning 56% ** 61% ** 51%* 25%
Social Functioning 29% 34% 24% 25%
Positive emotions 34% 37% 25% 25%
Negative emotions 38% 39% 37% 25%
  1. 1 25 th Percentiles of norm population are not exact 25% due to distribution of scale scores; percentiles approach 25th, ranging from 17th – 31st percentile.
  2. *p < 0.007: difference between CH patients and norm population according to Chi-square test **p < 0.0001: difference between CH patients and norm population according to Chi-square test.