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Table 5 Percentage at risk for impaired health related quality of life (TACQoL): patients with congenital hypothyroidism (CH) versus the norm population

From: Health- related quality of life and self-worth in 10-year old children with congenital hypothyroidism diagnosed by neonatal screening

 

Total CH

Severe CH

Moderate/Mild CH

Norm population

Child-report

    
 

n = 82

n = 41

n = 41

n = 449

Physical Functioning

40%

46% *

34%

25%

Motor Functioning

48% **

50% *

46% *

25%

Autonomy

38% **

46% **

29%

25%

Cognitive functioning

40% *

57% **

25%

25%

Social Functioning

34%

41%

28%

25%

Positive emotions

45% *

42%

47% *

25%

Negative emotions

30%

36%

25%

25%

Parent-report

    
 

n = 82

n = 41

n = 41

n = 465

Physical Functioning

34%

37%

32%

25%

Motor Functioning

55% **

61% **

49%*

25%

Autonomy

27%

32%

22%

25%

Cognitive functioning

56% **

61% **

51%*

25%

Social Functioning

29%

34%

24%

25%

Positive emotions

34%

37%

25%

25%

Negative emotions

38%

39%

37%

25%

  1. 1 25 th Percentiles of norm population are not exact 25% due to distribution of scale scores; percentiles approach 25th, ranging from 17th – 31st percentile.
  2. *p < 0.007: difference between CH patients and norm population according to Chi-square test **p < 0.0001: difference between CH patients and norm population according to Chi-square test.