Table 1 Schedule of major study assessments

Diagnostic evaluation

Kiddie schedule of affective disorders – present/lifetime

X

Aberrant symptom checklist

X

Wechsler abbreviated scale of intelligence

X

Family history

X

Medical history

X

Urine drug screen

X

Psychiatric stability (blinded rating)

Clinical global impression – severity and improvement scales

X

X

X

Brief psychiatric rating scale for children

X

X

X

Major metabolic assessments

Weight, height (body mass index z-score)

X

X

X

X

X

X

X

X

X

X

X

Waist circumference

X

X

X

X

Fasting glucose, insulin

X

X

X

X

Optional OGTT

X

X

X

HDL, LDL, triglycerides

X

X

X

DEXA

X

X

X

Metabolic syndrome

X

X

X

Medication tracking

Pill count (study drug) and self-report

X

X

X

X

X

X

X

X

X

Drug level (SGA, metformin)*

X

X

X

Review of co-prescribed and OTC medication

Adverse event/safety monitoring

Barnes Akathisia scale

X

X

X

X

X

X

X

X

X

X

X

Simpson Angus extrapyramidal symptoms scale

X

X

X

X

X

X

X

X

X

X

X

Abnormal involuntary movement scale

X

X

X

ECG

X

X

Urine pregnancy (females)

X

X

X

X

X

X

X

X

HLE review

X

X

X

X

X

X

X

X

X

X