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Table 1 Schedule of major study assessments

From: Improving metabolic parameters of antipsychotic child treatment (IMPACT) study: rationale, design, and methods

Assessment Screening 0 1 2 4 6 8 12 16 20 24
Diagnostic evaluation            
Kiddie schedule of affective disorders – present/lifetime X           
Aberrant symptom checklist X           
Wechsler abbreviated scale of intelligence X           
Family history X           
Medical history X           
Urine drug screen X           
Psychiatric stability (blinded rating)            
Clinical global impression – severity and improvement scales   X       X    X
Brief psychiatric rating scale for children   X       X    X
Major metabolic assessments            
Weight, height (body mass index z-score) X X X X X X X X X X X
Waist circumference X X       X    X
Fasting glucose, insulin X X       X    X
Optional OGTT   X       X    X
HDL, LDL, triglycerides   X       X    X
DEXA   X       X    X
Metabolic syndrome   X       X    X
Medication tracking            
Pill count (study drug) and self-report    X X X X X X X X X
Drug level (SGA, metformin)*   X       X    X
Review of co-prescribed and OTC medication            
Adverse event/safety monitoring            
Barnes Akathisia scale X X X X X X X X X X X
Simpson Angus extrapyramidal symptoms scale X X X X X X X X X X X
Abnormal involuntary movement scale   X      X     X
ECG X           X
Urine pregnancy (females) X X    X   X X X X X
HLE review   X X X X X X X X X X