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Table 5 p values for rs10150277-ADHD (in males) and -mRNA associations

From: Male-specific, replicable and functional roles of genetic variants and cerebral gray matter volumes in ADHD: a gene-wide association study across KTN1 and a region-wide functional validation across brain

“SNP-ADHD” association

“SNP-mRNA” association

Risk allele

Discovery sample (ABCD)

Replication sample (IMAGE)

Effective allele

GTEx

GTEx

BRAINEAC

GTEx

GTEx

GTEx

GTEx

Cortex

Limbic system

Basal ganglia

Frontal

Frontal

Occipital

Hippocampus

NAc

SNc

Cerebellum

C

0.028

0.010

T

0.014

0.020

2.2 × 10–4

0.010

0.026

0.001

0.001

  1. Risk allele is a major allele (f > 0.5). NAc, nucleus accumbens
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Child and Adolescent Psychiatry and Mental Health

ISSN: 1753-2000