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Table 4 Results of the univariate analysis of the polysomnographic findings in the whole group of subjects recruited in this study, sub-grouped by psychiatric diagnosis and antidepressant treatment class. All values are expressed as mean ± standard deviation

From: Frequency of antidepressant use and clinical characteristics of children and adolescents undergoing polysomnography: an observational study

 

Psychiatric Diagnosis Group

Antidepressant Class

 

None (n = 119)

Anxiety (n = 95)

Depression (n = 33)

Depression + Anxiety (n = 83)

p<

SSRI (n = 233)

SNRI (n = 22)

TCA (n = 9)

Atypical (n = 64)

p<

Age, years

12.5 ± 3.88

12.9 ± 3.07

15.4 ± 2.34

15.4 ± 2.21

0.000001

13.7 ± 2.99

16.0 ± 2.05

14.9 ± 1.96

12.7 ± 4.59

0.000023

Total sleep time, min

411.8 ± 86.85

420.3 ± 69.81

418.4 ± 88.51

402.2 ± 76.63

NS

412.7 ± 73.11

368.2 ± 114.15

392.1 ± 65.38

426.9 ± 86.36

NS

Sleep latency, min

31.5 ± 40.21

35.7 ± 40.34

27.1 ± 22.57

32 ± 31.28

NS

32.9 ± 35.63

34.9 ± 31.1

38.5 ± 27.66

29.7 ± 43.41

NS

Sleep efficiency, %

80.1 ± 16.78

81.1 ± 12.86

78.9 ± 18.6

82.9 ± 11.71

NS

80.8 ± 14.6

80.1 ± 15.73

82.9 ± 10.82

81.2 ± 15.8

NS

Stage N1, %

10.1 ± 7.08

10.1 ± 6.04

13.6 ± 7.94

13.4 ± 8.58

NS

11.7 ± 7.59

14.4 ± 8.3

8.2 ± 3.63

9.2 ± 6.48

NS

Stage N2, %

46.6 ± 12.96

47.3 ± 9.6

50.6 ± 10.36

49.4 ± 9.41

NS

48.4 ± 9.88

53.1 ± 13.0

50.0 ± 5.39

44.5 ± 13.44

NS

Stage N3, %

28.7 ± 12.79

27.2 ± 9.06

23.3 ± 6.49

21.8 ± 7.52

NS

25.3 ± 9.41

21.1 ± 10.17

28.1 ± 4.57

29.6 ± 12.95

NS

Stage R latency

172.3 ± 109.95

185.6 ± 104.86

187.8 ± 111.92

171 ± 96.91

NS

186.3 ± 101.02

191.4 ± 128.42

120.2 ± 71.49

148.5 ± 110.68

0.045

Stage R, %

14.7 ± 7.65

15.4 ± 6.94

12.5 ± 6.34

15.2 ± 6.09

NS

14.6 ± 6.75

11.4 ± 6.72

13.7 ± 5.05

16.7 ± 7.69

0.0076

PLMS index, n/hour

3.8 ± 8.74

3 ± 5.2

4.5 ± 8.1

3 ± 4.83

NS

4.0 ± 7.73

3.7 ± 5.06

2.5 ± 6.18

1.6 ± 3.14

NS

Obstructive AHI, n/hour

5.7 ± 16.84

3.6 ± 4.34

7.5 ± 12.55

4.1 ± 5.02

NS

5.1 ± 12.91

6.3 ± 7.4

1.5 ± 1.04

4.4 ± 6.73

NS

Central AHI, n/hour

2.3 ± 9.9

1.9 ± 10.32

0.8 ± 0.9

0.6 ± 0.97

NS

1.9 ± 9.65

0.9 ± 1.66

0.5 ± 0.6

0.9 ± 1.13

NS

  1. Note: the total number of subjects in each comparison can be different, depending on the presence of missing information in the database.
  2. SSRI = selective serotonin reuptake inhibitor; SNRI = serotonin and norepinephrine reuptake inhibitor; TCA = tricyclic antidepressant; PLMS = periodic leg movements during sleep; AHI = apnoea/hypopnea index; NS = not significant.
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Child and Adolescent Psychiatry and Mental Health

ISSN: 1753-2000