Table 1 Characteristics of the study cohort according to SSRI exposure during pregnancy (1997â2015)
From: Prenatal antidepressant exposure and emotional disorders until age 22: a danish register study
| Â | Exposed | Unexposed | Weighted- Unexposed | SMD* |
|---|---|---|---|---|
(Nâ=â15,651) | (Nâ=â896,816) | (nâ=â14,959) | Â | |
MOTHERS | N (%) | N (%) | N (%) | Â |
Age | Â | Â | Â | Â |
âMedian (IQR, years) | 30 (27â34) | 30 (27â33) | 30 (26â34) | 0.02 |
Parity | Â | Â | Â | Â |
âFirst childbirth | 6742 (43) | 388,114 (43) | 6,390 (43) | 0.01 |
â2â3 childbirth | 7770 (50) | 460,634 (52) | 7,536 (50) | 0.01 |
â4â+âchildbirth | 1084 (7.0) | 45,665 (5.1) | 984 (6.6) | 0.01 |
Body mass index | Â | Â | Â | Â |
âUnderweight | 560 (4.6) | 25,091 (4.3) | 505 (3.4) | 0.01 |
âNormal weight | 6689 (55) | 358,529 (62) | 6,447 (43) | 0.01 |
âOverweight | 2748 (23) | 122,910 (21) | 2,596 (17) | 0.01 |
âObese, class 1 | 1282 (11) | 46,557 (8.0) | 1,185 (7.9) | 0.01 |
âObese, class 2 & 3 | 866 (7.1) | 27,011 (4.7) | 788 (5.3) | 0.01 |
Smoking in pregnancy | Â | Â | Â | Â |
âNo smoking | 10,897 (73) | 706,880 (84) | 10,656 (71) | 0.04 |
âLight smoking (1â10 cigarettes/day) | 2775 (19) | 103,016 (12) | 2,541 (17) | 0.02 |
âHeavy smoking (11â+âcigarettes/day) | 1259 (8.4) | 34,332 (4.1) | 1,079 (7.2) | 0.03 |
Marital status | Â | Â | Â | Â |
âUnmarried | 8616 (55) | 426,635 (48) | 8,055 (54) | 0.02 |
âMarried/registered partnership | 7034 (45) | 470,065 (52) | 6,904 (46) | 0.02 |
Employment status | Â | Â | Â | Â |
âUn-employed | 6503 (42) | 246,077 (27) | 5,812 (39) | 0.06 |
âStudent | 940 (6.0) | 53,299 (5.9) | 925 (6.2) | 0.01 |
âEmployed | 7935 (51) | 577,870 (64) | 7,947 (53) | 0.05 |
âSelf-employed | 272 (1.7) | 19,513 (2.2) | 275 (1.8) | 0.01 |
Highest education | Â | Â | Â | Â |
âShort (7â10 years) | 4428 (29) | 164,174 (19) | 3,919 (26) | 0.05 |
âVocational training | 4357 (28) | 261,434 (30) | 4,292 (28) | 0.02 |
âMedium (11â13 years) | 2266 (15) | 139,282 (16) | 2,181 (15) | 0.00 |
âLong (13â+âyears) | 4279 (28) | 309,088 (35) | 4,274 (29) | 0.03 |
Income | Â | Â | Â | Â |
âFirst quartile (Lowest) | 5318 (34) | 203,342 (23) | 4,706 (32) | 0.05 |
âSecond quartile | 6227 (40) | 342,024 (38) | 6,143 (41) | 0.03 |
âThird quartile | 2934 (19) | 235,792 (26) | 2,931 (20) | 0.02 |
âForth quartile (Highest) | 1159 (7.4) | 114,734 (13) | 1,168 (7.8) | 0.02 |
Children | Â | Â | Â | Â |
Gender | Â | Â | Â | Â |
âMale | 8098 (52) | 460,255 (51) | 7,676 (51) | 0.01 |
âFemale | 7553 (48) | 436,563 (49) | 7,283 (49) | 0.01 |
Birth year | Â | Â | Â | Â |
â1997â2003 | 3017 (19) | 291,736 (33) | 2,966 (20) | 0.01 |
â2004â2009 | 6218 (40) | 322,830 (36) | 6,402 (43) | 0.06 |
â2010â2015 | 6416 (41) | 282,252 (31%) | 5,591 (37) | 0.07 |